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We sought to compare the results of the tractography with the HVMB anatomy described by Torrent-Guasp et al. DT-MRI vector field orientation: tractography is a technique inherited from the study of fluids, in which the orientation of vector fields stands for fluid stream directions, and thus reconstructions present no ambiguity. The previous pattern is reproduced along the left segment. My gfs roomate is thick af.org. The main property that clearly defines a streamline is that it is a curve tangential to the vector field at any point of such curve. El análisis objetivo de la arquitectura miocárdica mediante un método automatizado que incluye el miocardio completo y utiliza diferentes niveles de complejidad tridimensional revela una organización de las fibras en forma de estructura helicoidal continua que conforma ambos ventrículos.
As we track through lower streamlines, the lines are organized more horizontally but preserving a slight slope. By manually picking seeds at the basal level we obtained continuous paths connecting both ventricles and wrapping the whole myocardium. To deal with higher-level interpretations of the architectural organization of the heart we also looked for higher-level representations that can ease its interpretation and validation. This work also includes coloring techniques applied to our solution to ease the reading of the tractographic 3-dimensional models. My gfs roomate is thick af.reuters.com. To minimize this artifact, our streamlining method stops integration of streams with a large Runge-Kutta estimated reconstruction error. Heart tractography is seen as a reconstruction composed of several streamlines 28 (also known as fiber tracks in this field). Color maps tuned to longitudinal angulation convey more valuable information about muscle layers. The objective analysis of myocardial architecture by an automated method including the entire myocardium and using several 3-dimensional levels of complexity reveals a continuous helical myocardial fiber arrangement of both right and left ventricles, thus supporting the anatomical studies performed by F. DING.
It follows that most of the existing approaches 23–26, 34, 35 do not provide enough evidence widely accepted by the whole scientific community to either support or invalidate any particular architectural model. A clear pattern is observed where the reconstructed tracts on the epicardium are oriented towards the basal ring. Existing techniques reconstruct full heart anatomy using visual cues. The final dataset was arranged in about 256×256×108 arrays (depending on the scanned heart) and contains two kinds of data: geometry/scalar data and diffusion tensor data. The size of each voxel was about 312. Two of the most controversial approaches are the cardiac mesh model proposed by Anderson et al. Such disagreement is a direct consequence of a partial reconstruction of the heart fiber anatomy. During the last decade, a new imaging modality, diffusion tensor magnetic resonance imaging (DT-MRI), has enabled computational validation of the muscular structure of the heart. Animals and Pets Anime Art Cars and Motor Vehicles Crafts and DIY Culture, Race, and Ethnicity Ethics and Philosophy Fashion Food and Drink History Hobbies Law Learning and Education Military Movies Music Place Podcasts and Streamers Politics Programming Reading, Writing, and Literature Religion and Spirituality Science Tabletop Games Technology Travel. Create an account to follow your favorite communities and start taking part in conversations. 16 On the other side, the HVMB model states that the ventricular myocardium is a continuous anatomical helical layout of myocardial fibers, linking the ventricular anatomy to the well-described cardiac torsion mechanics.
These "summaries" are statistically complete so that the Gaussian smoothing keeps the contextual information before applying downsampling. In both models the main segments (labeled from A to G) of the helical architecture are clearly identified. This technique can be applied to the DT-MRI dataset to simplify its complexity. With fewer streamlines than on the previous captures, Figure 9 shows 3 populations where in this area streams coming from the apex start a noticeable ascent (fading from green to red coloration of the streams, denoting an increased slope) below the two other populations that are the beginning of the right segment at its connection with the pulmonary mplified Tractography. The use of visualizations with single tracts changes the way in which this structure can be viewed. The transition fiber loop from epicardium to endocardium is clearly seen in the left lateral segment of the left ventricular base. We compared such tracts to the proposed HVMB (Fig. Other techniques also have been explored, such as those in the work of Frindel et al. This methodology retains the main geometric features of the fiber tracts, making it easier to decipher the main properties of the architectural organization of the sults. The coloring indicates the sign of the fiber z-component (red for positive and green for negative) and, thus, its orientation. Fomblin has a low dielectric effect and minimal MRI signal, thereby increasing contrast and eliminating unwanted susceptibility artifacts near the boundaries of the heart. Usually applied to texture mapping, this technique is known as mipmapping, 30 based on the well-known pyramid representation.
Reduced textures are "summaries" of the original texture and are used to represent this texture at different scales. Indeed, DT-MRI provides a summary of the microscopic mesh enhancing the preferred pathway of the connected myocytes, which constitutes the concept of myocardial fiber. It is widely accepted that the myocardial fiber architecture plays a critical role in many functional aspects of the heart, such as electrical propagation 1, 2 or ventricular contraction. There are many factors that should be taken into account in order to obtain widely acceptable reconstructions and interpretations. In the present study, advanced computer graphics techniques were used to provide an objective and comprehensive description of the myocardial fiber architecture, as previously communicated, 21 and we introduce a multiresolution tractographic approach to provide a simplified and comprehensive understanding of the heart THODS. By downscaling two orders of magnitude of the original datasets and applying our streamlining, we get the simplified tractography shown in Figure 4.
Results show an unequivocal ventricular fiber connectivity describing a continuous muscular structure consisting of the two ventricles arranged in a double helical orientation. En el análisis de las tractografías de todo el espectro multiescalar, encontramos una correlación exacta en los detalles de bajo nivel, así como de la conceptualización abstracta de la disposición helicoidal continua de las fibras miocárdicas que conforman la arquitectura nclusiones. Las reconstrucciones a máxima resolución se han construido con 200 semillas y se componen de perfiles calculados sobre el volumen de vectores propios primarios obtenidos del tensor de difusión. Se han realizado reconstrucciones tractográficas automatizadas de datos de imágenes de resonancia magnética por tensor de difusión sin segmentar de corazones provenientes de la base de datos pública de la Johns Hopkins University. El objetivo de nuestro estudio es analizar objetivamente la arquitectura de las fibras miocárdicas mediante métodos avanzados de procesamiento gráfico por computadora aplicados a imágenes de resonancia magnética por tensor de difusión. Data completeness: it is undisputed that the basal ring is crucial to fully understand heart anatomy and function. Figure 12 shows a full-resolution tractographic reconstruction of muscle fibers obtained using our software. Visualization: comprehensive visualization of fiber tracts should involve a proper assignment of colors providing information about the orientation of the myocardial fibers. There is a clear similarity between the HVMB schematic model (Fig.
The long axis of the hearts was aligned with the z-axis of the scanner. Each heart was placed in an acrylic container filled with Fomblin, a perfluoropolyether (Ausimon; Thorofare, New Jersey, United States). We computed those streamlines using a fifth-order Runge-Kutta-Fehlbert 29 integration method that is able to provide successful results using variable integration steps based on error estimation. 18 This entangled structure is prone to hinder or even mislead the interpretation of "tracts" that define the muscular structure of the myocardium.